Enhanced Recovery After Surgery in Laparoscopic Cholecystectomy - A Systematic Review

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Enhanced Recovery After Surgery in Laparoscopic Cholecystectomy - A Systematic Review

Antonio Mihai Istrate, Dragos Serban, Horia Doran, Corneliu Tudor, Florin Bobirca, Dragos Davitoiu, Dan Dumitrescu, Andrei Popescu, Matei Popa Cherecheanu, Ciprian Tanasescu, Ion Motofei
Systematic Review, no. 3, 2024
Article DOI: 10.21614/chirurgia.2024.v.119.i.3.p.318
Background and Aim: Enhanced Recovery After Surgery (ERAS) is a modern concept that aims to improve the perioperative patient care by implementing an evidence-based, patient-centered team approach. This paper aims to analyze the outcome, variations and limits of the ERAS-protocols used for laparoscopic cholecystectomy.

Methods: We performed a systematic review on PubMed, Google Scholar, Web of Science to document the outcomes of applying various ERAS protocols in laparoscopic cholecystectomy (LC). After applying the inclusion and exclusion criteria, 8 papers, totaling 1453 patients that underwent LC, were included in the qualitative analysis. ERAS-protocols applied in those studies include various pre-, intra- and postoperative measures intended to boost the surgical recovery of the patients and shorten their hospital stay, without exposing them to hazardous encounters.

Results: Patients undergoing laparoscopic cholecystectomy within an ERAS-specific protocol are proven to have lower levels of postoperative pain, nausea and vomiting, with no statistically significant risk of postoperative complications. The postoperative results show that ERAS-laparoscopic cholecystectomy is a feasible and safe procedure, that may shorten the postoperative recovery after LC.

Conclusions: Further studies are needed to establish a consensus regarding the perioperative protocol, before implementing ERAS for LC in clinical routine.

Keywords: enhanced recovery after surgery (ERAS), laparoscopic cholecystectomy, minimally invasive, postoperative pain, outcomes