Clinical and Paraclinical Criteria of Patient Selection for the Non-operative Treatment in Completely Responsive Rectal Cancer (after Neoadjuvant Radiochemotherapy)A.M. Marincaş, V.M. Prunoiu, E. Brătucu, C. Cirimbei, S. Ionescu, R. Buzatu, N.D. Straja
Original article, no. 4, 2015
Introduction: Neoadjuvant radiotherapy is included in thetreatment protocols for rectal tumors in stages >= T3. The useof neoadjuvant radiotherapy allowed the limit of surgicaloncologic safety margin to decrease with 1-2 cm and theabdominoperineal resection to be able to be performed intumors situated at 4 cm from the anal verge. This modification of the treatment strategy increased the use of low, ultra low andcolo-anal anastomoses. Goal: Through the analysis of these types of anastomoses andof the disadvantages of the abdomino-perineal resection, we aimed at performing a study on the patients which responded completely to radiotherapy by taking into account the criteria of oncologic safety and the sparing of the patients from surgical complications. Material and method: We performed a retrospective study on171 patients with rectal cancer treated in the 1st Clinic of Surgery from the Bucharest Oncology Institute between October 2007 and December 2013. Results: 141 patients received radiotherapy, out of which 9 responded completely. 5 of those 9 were not operated on and after variable clinical and paraclinical follow up (2-6 years),they did not present with local recurrence. Conclusions: Not performing surgery in the patients withrectal cancer with a complete response to radiotherapy is a good solution and must be taken after a correct informationof the patient about rectal surgery with the condition of strictly observing the selection criteria of the patients.