The Value of Serum Bilirubin Level and of White Blood Cell Count as Severity Markers for Acute Appendicitis

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The Value of Serum Bilirubin Level and of White Blood Cell Count as Severity Markers for Acute Appendicitis

B. Socea, A. Carâp, M. Rac-Albu, V. Constantin
Original article, no. 6, 2013
Discussions regarding the correlations between elevated whiteblood cell levels and clinical and pathological stages of acuteappendicitis are well known. Recent studies show that a highlevel of serum bilirubin could emerge as a prognostic markerfor gangrenous or perforated stages of acute appendicitis. Westudied the correlations between anatomical and pathologicalstages of acute appendicitis and white blood cell count, serumtotal bilirubin, and indirect serum bilirubin on a large series ofcases, in the course of one year, in our department. Althoughthere being a correlation between severe forms of acuteappendicitis (gangrenous, perforated), elevated white bloodcell count, elevated serum bilirubin (mostly the indirectfraction), none of the indicators proved to have a definitivediagnostic value. Cases with perforation and localized generalized peritonitis are more frequently associated withelevated bilirubin levels.